News & Updates News WATCH OUR NEW B-RAF ANIMATED VIDEO Melanoma is the most serious form of skin cancer and the fifth most common cancer in the UK, with over 40 cases diagnosed every day. If detected early melanoma is almost always treatable but melanoma is a complex disease and multiple gene alterations have been found to play a role in its progression. The three most common gene mutations in melanoma are BRAF, NRAS and c-KIT. Of these, the BRAF mutation is most common: around 40-50% of melanoma patients have it. There are treatments available that specifically target this type of mutation and a test to determine your BRAF status will be carried out when you are diagnosed. You should be told the result to help decide the best form of treatment. This short animation explains what B-Raf is and why it matters! Pierre FABRE provided a restricted grant for this video to be made. This was a restricted grant and Pierre FABRE did not have any input into the content or review of the video.